Article
Titration of repeat-induced point mutation (RIP) by chromosome segment duplications in Neurospora crassa.
Genetica - 1 Nov 2008
Singh Parmit K, Kasbekar Durgadas P
Abstract excerpt
Repeat-induced point mutation (RIP) is a hypermutational process that alters duplicated DNA sequences in Neurospora crassa. In previous studies, five of six large ( > 100 kb) chromosome segment duplications (Dp's) examined were shown to dominantly suppress RIP in smaller (< 5 kb) duplications. The suppressor duplications were > 270 kb, whereas the lone non-suppressor duplication was approximately 117 kb. We have...
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