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Article

Supramolecular Host–Guest Interaction for Labeling and Detection of Cellular Biomarkers

24 Nov 2011

Abstract excerpt

Be my guest: A supramolecular host-guest interaction is utilized for highly efficient bioorthogonal labeling of cellular targets. Antibodies labeled with a cyclodextrin host molecule bind to adamantane-labeled magnetofluorescent nanoparticles (see picture) and provide an amplifiable strategy for biomarker detection that can be adapted to different diagnostic techniques such as molecular profiling or magnetic cell...

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PMID: 22113923
DOI: 10.1002/anie.201105670

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