Article
Transcriptional analysis of the HeT-A retrotransposon in mutant and wild type stocks reveals high sequence variability at Drosophila telomeres and other unusual features.
BMC genomics - 23 Nov 2011
Piñeyro David, López-Panadès Elisenda, Lucena-Pérez María, Casacuberta Elena
Abstract excerpt
BACKGROUND: Telomere replication in Drosophila depends on the transposition of a domesticated retroelement, the HeT-A retrotransposon. The sequence of the HeT-A retrotransposon changes rapidly resulting in differentiated subfamilies. This pattern of sequence change contrasts with the essential function with which the HeT-A is entrusted and brings about questions concerning the extent of sequence variability, the...
Topics
- Animals
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Products, gag
- Genetic Variation
- Male
- Mutation
- Retroelements
- Sequence Analysis, DNA
- Telomere