Article
Modelling the contribution of family history and variation in single nucleotide polymorphisms to risk of schizophrenia: a Danish national birth cohort-based study.
Schizophrenia research - 1 Feb 2012
Agerbo Esben, Mortensen Preben B, Wiuf Carsten, Pedersen Michael S, McGrath John, Hollegaard Mads V, Nørgaard-Pedersen Bent, Hougaard David M, Mors Ole, Pedersen Carsten B
Abstract excerpt
BACKGROUND: Epidemiological studies indicate that having any family member with schizophrenia increases the risk of schizophrenia in the probands. However, genome-wide association studies (GWAS) have accounted for little of this variation. The aim of this study was to use a population-based sample to explore the influence of single-nucleotide polymorphisms (SNPs) on the excess schizophrenia risk in offspring of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.