Article
Promoter regulation by distinct mechanisms of functional interplay between lysine acetylase Rtt109 and histone chaperone Asf1.
Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 2011
Lin Ling-ju, Schultz Michael C
Abstract excerpt
The promoter activity of yeast genes can depend on lysine 56 (K56) acetylation of histone H3. This modification of H3 is performed by lysine acetylase Rtt109 acting in concert with histone chaperone Asf1. We have examined the contributions of Rtt109, Asf1, and H3 K56 acetylation to nutrient regul...
Topics
- Acetylation
- Arginase
- Cell Cycle Proteins
- Chromatin Immunoprecipitation
- Culture Media
- Gene Expression Regulation, Fungal
- Histone Acetyltransferases
- Histones
- Lysine
- Molecular Chaperones
- Mutation
- Promoter Regions, Genetic
- Protein Binding
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins