Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir

1 Apr 2004

Abstract excerpt

OBJECTIVE: Although most uninfected infants born to women infected with HIV-1 show no clinical evidence of mitochondrial compromise, mitochondrial dysfunction has been reported in children born to women receiving zidovudine and/or lamivudine during pregnancy. In this pilot study we examined mitochondrial integrity in HIV-1-uninfected infants born to HIV-1-infected women receiving Combivir during pregnancy....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV-related health complications and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15096804
DOI: 10.1097/00002030-200404300-00009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to CombivirPMID 15096804Read ↗

Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor‐induced mitochondrial toxicitySemantic proximity Read ↗

Perinatal outcomes, mitochondrial toxicity and apoptosis in HIV-treated pregnant women and in-utero-exposed newbornSemantic proximity Read ↗

Long-Term Mitochondrial Toxicity in HIV-Uninfected Infants Born to HIV-Infected MothersSemantic proximity Read ↗

Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stressSemantic proximity Read ↗

Short Communication: Transplacental Nucleoside Analogue Exposure and Mitochondrial Parameters in HIV-Uninfected ChildrenSemantic proximity Read ↗

Placental Mitochondrial Toxicity, Oxidative Stress, Apoptosis, and Adverse Perinatal Outcomes in HIV Pregnancies Under Antiretroviral Treatment Containing ZidovudineSemantic proximity Read ↗

A brief overview of mechanisms of mitochondrial toxicity from NRTIs.Semantic proximity Read ↗

Mitochondrial dysfunction following perinatal exposure to nucleoside analoguesSemantic proximity Read ↗

HIV and mitochondrial toxicity in childrenSemantic proximity Read ↗

Neonatal HIV prophylaxis accelerates the clinical progression of MPV-17 mitochondrial neurohepatopathySemantic proximity Read ↗

Placenta and Cord Blood Mitochondrial DNA Toxicity in HIV-Infected Women Receiving Nucleoside Reverse Transcriptase Inhibitors During PregnancySemantic proximity Read ↗

Progressive Mitochondrial Compromise in Brains and Livers of Primates Exposed In Utero to Nucleoside Reverse Transcriptase Inhibitors (NRTIs)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.