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Article

DNA family shuffling within the chicken avidin protein family - A shortcut to more powerful protein tools.

Journal of biotechnology - 1 Jan 2012

Niederhauser Barbara, Siivonen Joonas, Määttä Juha A, Jänis Janne, Kulomaa Markku S, Hytönen Vesa P

Abstract excerpt

Avidins represent an interesting group of proteins showing high structural similarity and ligand-binding properties but low similarity in primary structure. In this study, we show that it is possible to create functional chimeric proteins from the avidin protein family when applying DNA family shuffling to the genes of the avidin protein family: avidin, avidin related gene 2 and biotin-binding protein A. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22100264
DOI: 10.1016/j.jbiotec.2011.10.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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