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Article

Molecular basis and bleeding manifestations of factor XI deficiency in 11 Turkish families.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2015

Keskin Ebru Ylmaz, Gürsel Türkiz, Kaya Zühre, Dai Letian, Koçak Ülker, Yenicesu İdil, Belen Fatma Burcu, Mitchell Michael

Abstract excerpt

Factor XI (FXI) deficiency is an autosomal bleeding disorder characterized by variable bleeding tendency. In the present study, the gene encoding FXI (F11) was analyzed by direct sequencing in 33 individuals belonging to 11 unrelated Turkish families, and the bleeding tendency was quantitatively assessed by means of a bleeding questionnaire in 27 individuals with low FXI clotting activity and/or mutated F11 gene....

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PMID: 25158988
DOI: 10.1097/MBC.0000000000000185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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