Article
[Association of single nucleotide polymorphism in human CYP8B1 gene with gallstone disease].
Zhonghua yi xue za zhi - 16 Aug 2011
Qin Jian, Jiang Zhao-yan, Niu Zhen-min, Zhang Kai-yue, Hua Qi, Jiang Zhi-hong, Wang Yi, Huang Wei, Han Tian-quan, Zhang Sheng-dao
Abstract excerpt
OBJECTIVE: To identify the single nucleotide polymorphisms of human CYP8B1gene and explore the association of some of these SNPs with gallstone disease in Chinese population. METHODS: The exon and part of promoter were sequenced by a fluorescent labeling automatic method to identify and characterize the SNPs in Chinese population. For SNPs with an allelic frequency of over 10%, a case-control study was performed...
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