Is PPARα intron 7 G/C polymorphism associated with muscle strength characteristics in nonathletic young men?

doi:10.1111/j.1600-0838.2011.01406.x

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Article

Is PPARα intron 7 G/C polymorphism associated with muscle strength characteristics in nonathletic young men?

Scandinavian journal of medicine & science in sports - 1 Aug 2013

Broos S, Windelinckx A, De Mars G, Huygens W, Peeters M W, Aerssens J, Vlietinck R, Beunen G P, Thomis M A

Abstract excerpt

Peroxisome proliferator-activated receptor alpha (PPARα), a ligand-dependent transcription factor, regulates fatty acid metabolism in heart and skeletal muscle. The intron 7 G/C polymorphism (rs4253778) has been associated with athletic performance. The rare C-allele was predominant in power athletes, whereas the G-allele was more frequent in endurance athletes. In the present study, we investigated the...

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PMID: 22092351
DOI: 10.1111/j.1600-0838.2011.01406.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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