Article
Stool DNA testing for the detection of pancreatic cancer: assessment of methylation marker candidates.
Cancer - 15 May 2012
Kisiel John B, Yab Tracy C, Taylor William R, Chari Suresh T, Petersen Gloria M, Mahoney Douglas W, Ahlquist David A
Abstract excerpt
BACKGROUND: Pancreatic cancer (PanC) presents at late stage with high mortality. Effective early detection methods are needed. Aberrantly methylated genes are unexplored as markers for noninvasive detection by stool testing. The authors aimed to select discriminant methylated genes and to assess accuracy of these and mutant KRAS in stool to detect PanC. METHODS: Nine target genes were assayed by real-time...
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