Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of NOG in esophageal atresia and tracheoesophageal fistula patients.

Pediatric surgery international - 1 Apr 2012

Murphy Andrew J, Li Yina, Pietsch Joshua B, Chiang Chin, Lovvorn Harold N

Abstract excerpt

PURPOSE: The NOG protein is a secretory antagonist of bone morphogenetic proteins (BMPs). Nog-/- mouse embryos demonstrate proximal esophageal atresia (EA) and distal tracheoesophageal fistula (TEF) compatible with the most common configuration of EA/TEF observed in humans. Four microdeletions that span the NOG locus at 17q22 have been described in human patients having EA/TEF. We investigated the incidence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carrier Proteins
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to TEF gene

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 22083168
DOI: 10.1007/s00383-011-3022-1
PMCID: PMC4148071

Genes

NOG
TEF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of NOG in esophageal atresia and tracheoesophageal fistula patients.PMID 22083168Read ↗

Esophageal atresia/tracheoesophageal fistula and proximal symphalangism in a patient with a NOG nonsense mutation.Semantic proximity Read ↗

Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresiaSemantic proximity Read ↗

A novel mutation in the gene encoding noggin is not causative in human neural tube defects.Semantic proximity Read ↗

Molecular analysis of the Noggin (NOG) gene in holoprosencephaly patients.Semantic proximity Read ↗

Teunissen-Cremers syndrome: a clinical, surgical, and genetic report.Semantic proximity Read ↗

Genetic and clinical phenotypic analysis of familial stapes sclerosis caused by an NOG mutation.Semantic proximity Read ↗

Identification of three novel mutations of the noggin gene in patients with fibrodysplasia ossificans progressiva.Semantic proximity Read ↗

Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway.Semantic proximity Read ↗

Heterozygous mutations in the gene encoding noggin affect human joint morphogenesis.Semantic proximity Read ↗

Proximal symphalangism, hyperopia, conductive hearing impairment, and the NOG gene: 2 new mutations.Semantic proximity Read ↗

Mutations of the noggin (NOG) and of the activin A type I receptor (ACVR1) genes in a series of twenty-seven French fibrodysplasia ossificans progressiva (FOP) patients.Semantic proximity Read ↗

BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.