Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNAs in mutagenesis, genomic instability, and DNA repair.

Seminars in oncology - 1 Dec 2011

Landau Dan-Avi, Slack Frank J

Abstract excerpt

MicroRNAs (miRNAs) are aiding our understanding of cancer biology, and are now coming close to therapeutic use as well. Here, we focus specifically on the interaction between miRNAs and genomic instability. MiRNA regulation is essential to many cellular processes, and escape from this regulatory network seems to be a common characteristic of malignant transformation. Genomic instability may preferentially target...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to DNA Repair
Share to Epigenesis, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Genomic Instability

Share to MicroRNAs

Share to Mutagenesis

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 22082760
DOI: 10.1053/j.seminoncol.2011.08.003
PMCID: PMC3217196

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNAs in mutagenesis, genomic instability, and DNA repair.PMID 22082760Read ↗

Genetic and epigenetic alterations of microRNAs and implications for human cancers and other diseases.Semantic proximity Read ↗

Genomic Instability and CancerSemantic proximity Read ↗

microRNAs in cancer: from bench to bedside.Semantic proximity Read ↗

microRNAs in Cancer Cell Response to Ionizing RadiationSemantic proximity Read ↗

The involvement of microRNAs in malignant transformation.Semantic proximity Read ↗

Multiple pathways leading to genomic instability and tumorigenesis.Semantic proximity Read ↗

Exploring Mechanisms of MicroRNA Downregulation in Cancer.Semantic proximity Read ↗

miRNA regulation is important for DNA damage repair and recognition in malignant pleural mesotheliomaSemantic proximity Read ↗

Genomic instability: on the birth and death of cancer.Semantic proximity Read ↗

Genomic instability and tumor progression: mechanistic considerations.Semantic proximity Read ↗

Interplay between the miRNome and the epigenetic machinery: Implications in health and disease.Semantic proximity Read ↗

miRISC inhibition causes mitotic defects and synergizes with genotoxic agents in cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.