Article
New Perspectives in Colorectal Cancers Treatment, the Role of MicroRNAs.
Current drug targets - 1 Jan 2024
Belova Victoria A, Spirina Liudmila V, Avgustinovich Alexandra V, Afanas'ev Sergey G, Volkov Maxim Y, Azovsky Daniil I, Volkov Alexander M, Klyushina Tatyana S
Abstract excerpt
The main epidemiological and clinical data on colorectal cancer, as well as the features of molecular pathology, are discussed in the literature review. Efforts are being putto identify promising targets, particularly small non-coding nucleotide sequences, which can lead to new treatments for this disease. The discovery of significant mutations that contribute to the development of colorectal tumors is a major...
Topics
- Humans
- Colorectal Neoplasms
- MicroRNAs
- Epigenesis, Genetic
- Gene Expression Regulation, Neoplastic
- Mutation
- Molecular Targeted Therapy
- Prognosis
- Biomarkers, Tumor
- Antineoplastic Agents