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Article

Correlated mutations via regularized multinomial regression.

BMC bioinformatics - 14 Nov 2011

Sreekumar Janardanan, ter Braak Cajo J F, van Ham Roeland C H J, van Dijk Aalt D J

Abstract excerpt

BACKGROUND: In addition to sequence conservation, protein multiple sequence alignments contain evolutionary signal in the form of correlated variation among amino acid positions. This signal indicates positions in the sequence that influence each other, and can be applied for the prediction of intra- or intermolecular contacts. Although various approaches exist for the detection of such correlated mutations, in...

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PMID: 22082126
DOI: 10.1186/1471-2105-12-444
PMCID: PMC3247924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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