Article
Serpin polymerization in vitro.
Methods in enzymology - 1 Jan 2011
Huntington James A, Yamasaki Masayuki
Abstract excerpt
Serpin polymerization is an event which generally occurs within living tissue as a consequence of a folding defect caused by point mutations. Major advances in cell biology and imaging have allowed detailed studies into subcellular localization, processing, and clearance of serpin polymers, but to understand the molecular basis of the misfolded state and polymeric linkage, it has been and continues to be...
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