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Article

Computational methods for studying serpin conformational change and structural plasticity.

Methods in enzymology - 1 Jan 2011

Kass Itamar, Reboul Cyril F, Buckle Ashley M

Abstract excerpt

Currently, over a hundred high-resolution structures of serpins are available, exhibiting a wide range of conformations. However, our understanding of serpin dynamics and conformational change is still limited, mainly due to challenges of monitoring structural changes and characterizing transient conformations using experimental methods. Insight can be provided, however, by employing theoretical and computational...

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PMID: 22078540
DOI: 10.1016/B978-0-12-385950-1.00014-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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