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Article

Covariation of major and minor viral capsid proteins in norovirus genogroup II genotype 4 strains.

Journal of virology - 1 Jan 2012

Chan Martin Chi-Wai, Lee Nelson, Ho Wing-Shan, Law Carmen Oi-Kwan, Lau Terrence Chi-Kong, Tsui Stephen Kwok-Wing, Sung Joseph Jao-Yiu

Abstract excerpt

We report sequence hypervariability in the viral protein 1 (VP1) interaction domain of VP2 in the norovirus (NoV) genogroup II genotype 4 (GII.4) lineage on 3 levels: (i) the global evolution of pandemic/epidemic strains from the mid-1970s through post-2006, (ii) the local emergence of an epidemic strain, and (iii) an immunocompromised patient chronically shedding NoV. When a quantitative yeast two-hybrid assay...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22072750
DOI: 10.1128/JVI.00228-11
PMCID: PMC3255813

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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