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Article

Out-of-sync evolutionary patterns and mutual interplay of major and minor capsid proteins in norovirus GII.2.

The Journal of general virology - 1 Sept 2024

Xu Ruiquan, Xue Liang, Wang Jingmin, Chen Yiqing, Cao Yingwen, Gao Junshan, Gao Hui, Du Qingyao, Kou Xiaoxia, Yu Lin

Abstract excerpt

Human noroviruses are the most common cause of viral gastroenteritis, resulting annually in 219 000 deaths and a societal cost of $60 billion, and no antivirals or vaccines are available. The minor capsid protein may play a significant role in the evolution of norovirus. GII.4 is the predominant genotype of norovirus, and its VP2 undergoes epochal co-evolution with the major capsid protein VP1. Since the sudden...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39331030
DOI: 10.1099/jgv.0.002024
PMCID: PMC11430271

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