Article
PCR for monitoring of minimal residual disease in hematologic malignancy.
Clinica chimica acta; international journal of clinical chemistry - 18 Jan 2012
Matsuda Kazuyuki, Sugano Mitsutoshi, Honda Takayuki
Abstract excerpt
Monitoring minimal residual disease (MRD) is useful to evaluate therapeutic response and risk of relapse in patients with hematologic malignancy. Currently available quantitative MRD assays are fluorescence in situ hybridization of chromosomal aberrations; multiparameter flow cytometry of leukemia-associated immunophenotypes; and quantitative polymerase chain reaction (qPCR) analysis of fusion genes,...
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