Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TIMP1 Contributes to Ovarian Anomalies in Both an MMP-Dependent and -Independent Manner in a Rat Model1

4 Nov 2011

Abstract excerpt

Ovulatory dysfunction occurs in women with endometriosis, yet the mechanisms are unknown. We have shown that endometriotic lesions synthesize and secrete tissue inhibitor of metalloproteinase (TIMP) 1 into the peritoneal cavity in humans and a rat model of endometriosis, where excess TIMP1 localizes in the ovarian theca in endometriosis and modulating peritoneal TIMP1 alters ovarian dynamics. Here, we evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Endometriosis Research and Treatment
Share to Uterine Myomas and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22053095
DOI: 10.1095/biolreprod.111.094680

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TIMP1 Contributes to Ovarian Anomalies in Both an MMP-Dependent and -Independent Manner in a Rat Model1PMID 22053095Read ↗

Functions for proteinases in the ovulatory process.Semantic proximity Read ↗

Spotlight on Proteases: Roles in Ovarian Health and DiseaseSemantic proximity Read ↗

miR-191 Modulates Malignant Transformation of Endometriosis Through Regulating TIMP3Semantic proximity Read ↗

Matrix Metalloproteinases and Their Inhibitors in the Pathogenesis of Epithelial Differentiation, Vascular Disease, Endometriosis, and Ocular Fibrotic PterygiumSemantic proximity Read ↗

The TIMP protein family: diverse roles in pathophysiologySemantic proximity Read ↗

Inhibitory effect of AQP1 silencing on adhesion and angiogenesis in ectopic endometrial cells of mice with endometriosis through activating the Wnt signaling pathwaySemantic proximity Read ↗

Disruption of the TIMP-1 gene product is associated with accelerated endometrial gland formation during early postnatal uterine development.Semantic proximity Read ↗

Whole Organism Profiling of the Timp Gene FamilySemantic proximity Read ↗

Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat ModelSemantic proximity Read ↗

The Eutopic Endometrium Proteome in Endometriosis Reveals Candidate Markers and Molecular Mechanisms of PhysiopathologySemantic proximity Read ↗

Collagenases MMP-1, MMP-13, and Tissue Inhibitors TIMP-1, TIMP-2: Their Role in Healthy and Complicated Pregnancy and Potential as Preeclampsia Biomarkers—A Brief ReviewSemantic proximity Read ↗

How transcription factors regulate apoptosis in endometriosis (Review)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.