Clonal segregation of oligodendrocytes and astrocytes during in vitro differentiation of glial progenitor cells.

doi:10.1002/glia.440060407

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Article

Clonal segregation of oligodendrocytes and astrocytes during in vitro differentiation of glial progenitor cells.

Glia - 1 Jan 1992

Lubetzki C, Goujet-Zalc C, Demerens C, Danos O, Zalc B

Abstract excerpt

To study the clonal lineage of the glial progenitor population, isolated from newborn rat brain (Lubetzki et al. J Neurochem 56:671, 1991), we combined somatic transgenesis using a retroviral vector encoding a modified bacterial beta-galactosidase with nuclear localization, and triple immunofluorescence labeling with A2B5, anti-galactosylceramide, and anti-glial acidic fibrillary protein antibodies. This allowed...

Topics

Animals
Astrocytes
Cattle
Cell Differentiation
Cell Line
Cell Separation
Clone Cells
Culture Media
Escherichia coli
Fetal Blood
Genetic Vectors
Neuroglia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligodendroglia

Phenotype

Rats

Retroviridae

Stem Cells

beta-Galactosidase

Source

Open in PubMed

Identifiers

PMID: 1464461
DOI: 10.1002/glia.440060407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1464461-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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