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Article

Inherited liver shunts in dogs elucidate pathways regulating embryonic development and clinical disorders of the portal vein.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2012

van Steenbeek Frank G, van den Bossche Lindsay, Leegwater Peter A J, Rothuizen Jan

Abstract excerpt

Congenital disorders of the hepatic portal vasculature are rare in man but occur frequently in certain dog breeds. In dogs, there are two main subtypes: intrahepatic portosystemic shunts, which are considered to stem from defective closure of the embryonic ductus venosus, and extrahepatic shunts,...

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PMID: 22052005
DOI: 10.1007/s00335-011-9364-0
PMCID: PMC3275728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22052005-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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