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The genetics of portal hypertension: Recent developments and the road ahead

18 Sept 2023

Abstract excerpt

Portal hypertension (PH), defined as a pathological increase in the portal vein pressure, has different aetiologies and causes. Intrahepatic PH is mostly secondary to the presence of underlying liver disease leading to cirrhosis, characterized by parenchymal changes with deregulated accumulation of extracellular matrix and vascular abnormalities; liver sinusoidal endothelial cells and hepatic stellate cells are...

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PMID: 37718732
DOI: 10.1111/liv.15732

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