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Article

SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell

17 Mar 2011

Abstract excerpt

SRY-related HMG-box gene 2 (SOX2) is one of the key regulatory genes that maintain the pluripotency and self-renewal properties in embryonic stem cells. Here we used immunohistochemistry to analyze the expression of SOX2 in human prostate tissues and found it contributed to tumorigenesis and correlated with histologic grade and Gleason score. We further investigated SOX2's function in cell growth and apoptosis...

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PMID: 21415100
DOI: 10.1093/jmcb/mjr002

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SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cellPMID 21415100Read ↗

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