Article
Down-regulation of miR-7-5p and miR-548ar-5p predicts malignancy in indeterminate thyroid nodules negative for BRAF and RAS mutations.
Endocrine - 1 Jun 2022
Macerola Elisabetta, Poma Anello Marcello, Proietti Agnese, Rago Teresa, Romani Rossana, Vignali Paola, Ugolini Clara, Torregrossa Liborio, Basolo Alessio, Santini Ferruccio, Basolo Fulvio
Abstract excerpt
PURPOSE: The value of molecular markers in refining preoperative risk assessment of indeterminate thyroid nodules is being widely investigated. MicroRNAs (miRNA) are emerging as promising biomarkers for diagnostic and prognostic purposes. The aim of this study is to identify miRNAs specifically deregulated in mutation-negative indeterminate thyroid nodules. METHODS: Ninety-eight nodules preoperatively diagnosed...
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