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Article

Hansa: an automated method for discriminating disease and neutral human nsSNPs.

Human mutation - 1 Feb 2012

Acharya Vishal, Nagarajaram Hampapathalu A

Abstract excerpt

Variations are mostly due to nonsynonymous single nucleotide polymorphisms (nsSNPs), some of which are associated with certain diseases. Phenotypic effects of a large number of nsSNPs have not been characterized. Although several methods have been developed to predict the effects of nsSNPs as "disease" or "neutral," there is still a need for development of methods with improved prediction accuracies. We,...

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PMID: 22045683
DOI: 10.1002/humu.21642

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TPR

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