Article
Combined effect of low-penetrant SNPs on breast cancer risk.
British journal of cancer - 17 Jan 2012
Harlid S, Ivarsson M I L, Butt S, Grzybowska E, Eyfjörd J E, Lenner P, Försti A, Hemminki K, Manjer J, Dillner J, Carlson J
Abstract excerpt
BACKGROUND: Although many low-penetrant genetic risk factors for breast cancer have been discovered, knowledge about the effect of multiple risk alleles is limited, especially in women <50 years. We therefore investigated the association between multiple risk alleles and breast cancer risk as well as individual effects according to age-approximated pre- and post-menopausal status. METHODS: Ten previously...
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