Article
Targeted therapies for breast cancer.
The Journal of clinical investigation - 1 Oct 2011
Higgins Michaela J, Baselga José
Abstract excerpt
In recent years the description of well-defined molecular subtypes of breast cancer, together with the identification of the driving genetic alterations and signaling pathways, has led to the clinical development of a number of successful molecular targeted agents. This is best exemplified in the subset of HER2-amplified breast cancers, in which an increasing number of active agents are changing the natural...
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