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Article

CCR2 polymorphism in chronic renal failure patients requiring long-term hemodialysis.

Internal medicine (Tokyo, Japan) - 1 Jan 2011

Sezgin Ilhan, Koksal Binnur, Bagci Gokhan, Kurtulgan Hande Kucuk, Ozdemir Ozturk

Abstract excerpt

OBJECTIVE: A number of chemokines and chemokine receptors are produced by intrinsic renal cells as well as by infiltrating cells during renal inflammation. The CCR2 chemokine receptor mediates leukocyte chemoattraction in the initiation and amplification phase of renal inflammation. The polymorphism, CCR2-V64I, changes valine 64 of CCR2 to isoleucine. We aimed to determine the frequency of CCR2-V64I polymorphism...

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Share to Gene Frequency
Share to Isoleucine
Share to Kidney Failure, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, CCR2

Share to Renal Dialysis

Share to Time Factors

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Source

Identifiers

PMID: 22041342
DOI: 10.2169/internalmedicine.50.5119

Genes

CCR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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