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Inhibition of α Folate Receptor Resulting in a Reversal of Taxol Resistance in Nasopharyngeal Carcinoma

31 Oct 2011

Abstract excerpt

OBJECTIVE: To further determine the role of FOLR1 in taxol resistance of nasopharyngeal carcinoma (NPC) and whether inhibition of FOLR1 expression reverses the taxol-resistant phenotype. STUDY DESIGN: Correlation study between gene expression and cancer cell survival. SETTING: University hospital. SUBJECTS AND METHODS: Three taxol-resistant sub-cell lines with a different resistant index were established from the...

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PMID: 22041223
DOI: 10.1177/0194599811426260

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