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Article

Isolated GHD: investigation and implication of JAK/STAT related genes before and after rhGH treatment.

Pituitary - 1 Dec 2012

Trovato Letizia, Riccomagno Stefania, Prodam Flavia, Genoni Giulia, Walker Gillian E, Moia Stefania, Bellone Simonetta, Bona Gianni

Abstract excerpt

Isolated GH deficiency (IGHD) is a rare disorder that occurs as an idiopathic form in most cases. The pathway JAK/STAT promotes cellular growth and it could be implicated in this condition. In order to characterize IGHD in the pediatric population and identify genes differently expressed before and after GH therapy, we performed a quantitative evaluation of 84 genes related to the JAK/STAT pathway which, by...

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Source

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PMID: 22038029
DOI: 10.1007/s11102-011-0354-8

Genes

GHR
CRP
TNF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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