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Article

Isolation of the replication and partitioning regions of the Salmonella typhimurium virulence plasmid and stabilization of heterologous replicons.

Journal of bacteriology - 1 Sept 1990

Tinge S A, Curtiss R

Abstract excerpt

Although the virulence plasmid of Salmonella typhimurium has a copy number of one to two per chromosome, plasmid-free segregants are produced at a rate less than 10(-7) per cell per generation. Three regions appear to be involved in the maintenance of this virulence plasmid. The first two, repB and repC, are functional replicons hybridizing with IncFII and IncFI plasmids, respectively, neither exhibiting the...

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Identifiers

PMID: 2203747
DOI: 10.1128/jb.172.9.5266-5277.1990
PMCID: PMC213189

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