Article
Predictive models for subtypes of autism spectrum disorder based on single-nucleotide polymorphisms and magnetic resonance imaging.
Advances in medical sciences - 1 Jan 2011
Jiao Y, Chen R, Ke X, Cheng L, Chu K, Lu Z, Herskovits E H
Abstract excerpt
PURPOSE: Autism spectrum disorder (ASD) is a neurodevelopmental disorder, of which Asperger syndrome and high-functioning autism are subtypes. Our goal is: 1) to determine whether a diagnostic model based on single-nucleotide polymorphisms (SNPs), brain regional thickness measurements, or brain regional volume measurements can distinguish Asperger syndrome from high-functioning autism; and 2) to compare the SNP,...
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