Article
Do discordant cancers share familial susceptibility?
European journal of cancer (Oxford, England : 1990) - 1 May 2012
Hemminki Kari, Sundquist Jan, Brandt Andreas
Abstract excerpt
AIMS: Cancer syndromes manifest at many sites albeit with variable penetrance. Genome-wide association (GWA) studies have identified susceptibility loci shared by many types of cancer. Yet, a population level search for shared susceptibility between discordant cancers has been hampered because of lacking population sizes. METHODS: Over 1.1million patients in the nation-wide Swedish Family-Cancer Database were...
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