Article
Identification of allele-specific RNAi effectors targeting genetic forms of Parkinson's disease.
PloS one - 1 Jan 2011
Sibley Christopher R, Wood Matthew J A
Abstract excerpt
Parkinson's disease (PD) is a progressive neurological disorder affecting an estimated 5-10 million people worldwide. Recent evidence has implicated several genes that directly cause or increase susceptibility to PD. As well as advancing understanding of the genetic aetiology of PD these findings suggest new ways to modify the disease course, in some cases through genetic manipulation. Here we generated a...
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