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Article

Tailor-made RNAi knockdown against triplet repeat disease-causing alleles.

Proceedings of the National Academy of Sciences of the United States of America - 14 Dec 2010

Takahashi Masaki, Watanabe Shoko, Murata Miho, Furuya Hirokazu, Kanazawa Ichiro, Wada Keiji, Hohjoh Hirohiko

Abstract excerpt

Nucleotide variations, including SNPs, in the coding regions of disease genes are important targets for RNAi treatment, which is a promising medical treatment for intractable diseases such as triplet repeat diseases. However, the identification of such nucleotide variations and the design of siRN...

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Identifiers

PMID: 21098280
DOI: 10.1073/pnas.1012153107
PMCID: PMC3003091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21098280-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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