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Article

Parameter adaptations during phenotype transitions in progressive diseases.

BMC systems biology - 26 Oct 2011

Tiemann Christian A, Vanlier Joep, Hilbers Peter A J, van Riel Natal A W

Abstract excerpt

BACKGROUND: The study of phenotype transitions is important to understand progressive diseases, e.g., diabetes mellitus, metabolic syndrome, and cardiovascular diseases. A challenge remains to explain phenotype transitions in terms of adaptations in molecular components and interactions in underlying biological systems. RESULTS: Here, mathematical modeling is used to describe the different phenotypes by...

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PMID: 22029623
DOI: 10.1186/1752-0509-5-174
PMCID: PMC3354367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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