Article
Pathologic phenotyping of mutant mice.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Bronson Roderick T
Abstract excerpt
The easiest and cheapest way to analyze the phenotype of most knockout mice is to do a comprehensive necropsy and histopathologic examination of slides of all tissues. Once any lesion is found in a knockout mouse a vast contemporary and traditional literature can be searched for occurrences of similar lesions in other species, including human beings. This may provide further insights into the molecular and...
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