Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cause and effect considerations in diagnostic pathology and pathology phenotyping of genetically engineered mice (GEM).

ILAR journal - 1 Jan 2006

McKerlie Colin

Abstract excerpt

Over the next several decades, biology is embarking on its most ambitious project yet: to annotate the human genome functionally, prioritizing and focusing on those genes relevant to development and disease. Model systems are fundamental prerequisites for this task, and genetically engineered mice (GEM) are by far the most accessible mammalian system because of their anatomical, physiological, and genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to GEM gene
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Phenotype

Share to Rodent Diseases

Source

Identifiers

PMID: 16547372
DOI: 10.1093/ilar.47.2.156

Genes

GEM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cause and effect considerations in diagnostic pathology and pathology phenotyping of genetically engineered mice (GEM).PMID 16547372Read ↗

Internet and print resources to facilitate pathology analysis when phenotyping genetically engineered rodents.Semantic proximity Read ↗

Evaluating mutant mice: anatomic pathology.Semantic proximity Read ↗

The power of mouse models in the diagnostic odyssey of patients with rare congenital anomalies.Semantic proximity Read ↗

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice.Semantic proximity Read ↗

Standardized morphological phenotyping of mouse models of human diseases within the German Mouse Clinic.Semantic proximity Read ↗

Phenotyping of genetically engineered mice: humane, ethical, environmental, and husbandry issues.Semantic proximity Read ↗

Mouse phenogenomics, toolbox for functional annotation of human genome.Semantic proximity Read ↗

Pathology methods for the evaluation of embryonic and perinatal developmental defects and lethality in genetically engineered mice.Semantic proximity Read ↗

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.Semantic proximity Read ↗

Neuropathology of genetically engineered mice: consensus report and recommendations from an international forumSemantic proximity Read ↗

Introduction: Strategies for developing genetically modified mice.Semantic proximity Read ↗

The program for phenotyping of genetically modified animals at AstraZeneca.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.