Article
Adaptive cis-regulatory changes may involve few mutations.
Evolution; international journal of organic evolution - 1 Nov 2011
Razeto-Barry Pablo, Maldonado Karin
Abstract excerpt
A long-standing debate in evo-devo research concerns the relative role of protein-coding and cis-regulatory regions in adaptation. Recent studies of genetic adaptation have revealed that the number of substitutions contributing to phenotypic variation is lower in cis-regulatory than in structural regions, which has led to the idea that cis-regulatory regions are less important in phenotypic adaptation. However,...
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