Article
Genetic properties influencing the evolvability of gene expression.
Science (New York, N.Y.) - 6 Jul 2007
Landry Christian R, Lemos Bernardo, Rifkin Scott A, Dickinson W J, Hartl Daniel L
Abstract excerpt
Identifying the properties of gene networks that influence their evolution is a fundamental research goal. However, modes of evolution cannot be inferred solely from the distribution of natural variation, because selection interacts with demography and mutation rates to shape polymorphism and divergence. We estimated the effects of naturally occurring mutations on gene expression while minimizing the effect of...
Topics
- Binding Sites
- Evolution, Molecular
- Gene Expression
- Gene Expression Regulation, Fungal
- Gene Regulatory Networks
- Genes, Fungal
- Genetic Variation
- Linear Models
- Models, Genetic
- Mutation
- Oligonucleotide Array Sequence Analysis