Exploring potential sources of differential vulnerability and susceptibility in risk from environmental hazards to expand the scope of risk assessment.

Abstract excerpt

Genetic factors, other exposures, individual disease states and allostatic load, psychosocial stress, and socioeconomic position all have the potential to modify the response to environmental exposures. Moreover, many of these modifiers covary with the exposure, leading to much higher risks in some subgroups. These are not theoretical concerns; rather, all these patterns have already been demonstrated in studies...

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