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Article

Generation of a genotype VII Newcastle disease virus vaccine candidate with high yield in embryonated chicken eggs.

Avian diseases - 1 Sept 2011

Hu Zenglei, Hu Shunlin, Meng Chun, Wang Xiaoquan, Zhu Jie, Liu Xiufan

Abstract excerpt

To generate a genotype VII Newcastle disease virus (NDV) vaccine with high yield in embryonated chicken eggs, we selected genotype VII NDV strain JS5/05, which possesses a high virus titer in embryos as the parental virus. Using reverse genetics, we generated a genetically tagged derivative (NDV/AI4) of JS5/05 by changing the amino acid sequence of the cleavage site of the F0 protein. Pathogenicity tests showed...

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Identifiers

PMID: 22017036
DOI: 10.1637/9633-122410-Reg.1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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