Article
Horizontal transmission of a human rotavirus vaccine strain--a randomized, placebo-controlled study in twins.
Vaccine - 28 Nov 2011
Rivera Luis, Peña Lourdes Mendez, Stainier Isabelle, Gillard Paul, Cheuvart Brigitte, Smolenov Igor, Ortega-Barria Eduardo, Han Htay Htay
Abstract excerpt
Transmission of excreted vaccine-derived infectious virus from vaccinated to unvaccinated individuals is possible within close contacts. This randomized (1:1), double-blind study evaluated the potential for transmission of human rotavirus vaccine strain, HRV (Rotarix™) from vaccine recipients to unvaccinated close contacts (twins). 100 pairs of healthy twins aged 6-14 weeks at the time of Dose 1 of HRV...
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