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Suppression of the invasion and migration of cancer cells by SERPINB family genes and their derived peptides

6 Oct 2011

Abstract excerpt

Apart from SERPINB2 and SERPINB5, the roles of the remaining 13 members of the human SERPINB family in cancer metastasis are still unknown. In the present study, we demonstrated that most of these genes are differentially expressed in tumor tissues compared to matched normal tissues from lung or breast cancer patients. Overexpression of each SERPINB gene effectively suppressed the invasiveness and motility of...

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Identifiers

PMID: 21993616
DOI: 10.3892/or.2011.1497

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