Article
CCL2/MCP-I genotype-phenotype relationship in latent tuberculosis infection.
PloS one - 1 Jan 2011
Hussain Rabia, Ansari Ambreen, Talat Najeeha, Hasan Zahra, Dawood Ghaffar
Abstract excerpt
Among the known biomarkers, chemokines, secreted by activated macrophages and T cells, attract groups of immune cells to the site of infection and may determine the clinical outcome. Association studies of CCL-2/MCP-1 -2518 A/G functional SNP linked to high and low phenotypes with tuberculosis disease susceptibility have shown conflicting results in tuberculosis. Some of these differences could be due the...
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