Article
Age-Specific Association of CCL5 Gene Polymorphism with Pulmonary Tuberculosis: A Case-Control Study.
Genetic testing and molecular biomarkers - 1 May 2018
Varzari Alexander, Tudor Elena, Bodrug Nina, Corloteanu Andrei, Axentii Ecaterina, Deyneko Igor V
Abstract excerpt
OBJECTIVES: Chemokines play a key role in immune regulation and response, and have been implicated in the pathogenesis of tuberculosis (TB). In this study, we investigated whether functional polymorphisms of the chemokines CCL5, CCL2, and CXCL8 are associated with pulmonary TB in a Moldavian population. MATERIALS AND METHODS: A total of 250 patients with TB and 184 healthy controls were screened for CCL5 -403G/A...
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