Article
Joint effect of MCP-1 genotype GG and MMP-1 genotype 2G/2G increases the likelihood of developing pulmonary tuberculosis in BCG-vaccinated individuals.
PloS one - 25 Jan 2010
Ganachari Malathesha, Ruiz-Morales Jorge A, Gomez de la Torre Pretell Juan C, Dinh Jeffrey, Granados Julio, Flores-Villanueva Pedro O
Abstract excerpt
We previously reported that the -2518 MCP-1 genotype GG increases the likelihood of developing tuberculosis (TB) in non-BCG-vaccinated Mexicans and Koreans. Here, we tested the hypothesis that this genotype, alone or together with the -1607 MMP-1 functional polymorphism, increases the likelihood...
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