Article
Lack of association between rs1024611 (-2581 A/G) polymorphism in CC-chemokine Ligand 2 and susceptibility to pulmonary Tuberculosis in Zahedan, Southeast Iran.
Prague medical report - 1 Jan 2011
Naderi M, Hashemi M, Karami H, Moazeni-Roodi A, Sharifi-Mood B, Kouhpayeh H, Taheri M, Ghavami S
Abstract excerpt
Approximately 5-10% of subjects infected with Mycobacterium tuberculosis develop active tuberculosis. It has been proposed that genetic factors determine the host's vulnerability to tuberculosis. Chemokine (C-C motif) ligand 2 (CCL2), commonly known as monocyte chemoattractant protein-1 (MCP-1), plays a key role in protective immunity against M. tuberculosis. The present...
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